Significados de fibrous dysplasia em inglês

Histopathologic analysis by an experienced bone pathologist confirmed fibrous dysplasia in all patients.

In this paper the authors examine current findings on the etiology of fibrous dysplasia.

Case descriptions: We report four unusual cases of fibrous dysplasia with an aggressive radiographic appearance.

A case of monostotic fibrous dysplasia of a long bone of the hand is reported.

Sarcomas infrequently develop in osseous sites of fibrous dysplasia.

The cause of fibrous dysplasia is not understood.

GNAS1 mutation analysis has diagnostic value in screening patients with intramuscular myxoma and patients with fibrous dysplasia.

Bone lesions in fibrous dysplasia arise in the medullary canal and usually are confined to the bone.

Several studies have shown an increase of c-fos mRNA in the bone lesions of patients with fibrous dysplasia.

To our knowledge, this is the largest case report published regarding locally aggressive fibrous dysplasia arising outside the craniofacial skeleton.

However, the other patient exhibited an unusual hyperostotic change in the skull base mimicking fibrous dysplasia of the skull base.

Locally aggressive fibrous dysplasia with cortical destruction and extension into soft tissue in the absence of these two possibilities is extremely rare.

Clinical relevance: The locally aggressive variant of fibrous dysplasia may be confused with a malignant tumor or malignant degeneration of fibrous dysplasia.

Finally, at the end of the review, abnormalities in renal phosphate transport that are sometimes found in patients with polyostotic fibrous dysplasia are discussed.

There may be an increased incidence of malignant transformation in these individuals' dysplastic bones above that associated with patients suffering from fibrous dysplasia alone.

The authors emphasize the association of bone abnormalities and tuberous sclerosis and discuss the consideration of fibrous dysplasia as a component of this syndrome.